Pancreatic adenocarcinoma: Outstanding problems

Outstanding bile pigment problems.

In this review of the chemistry, biochemistry and chemical pathology of the bile pigments I am well aware that I shall ask many more questions than I am able to answer. It seems appropriate that the subject should be considered under the five headings: -Chemistry; Formation from Haem Proteins; Transport in the Blood; Conjugation and Transport to the Bile; and Changes in the Gut. I shall conclud...

Pancreatic Adenocarcinoma NCCN Pancreatic Adenocarcinoma Panel Members

Exocrine pancreatic adenocarcinoma in a toy breed dog

A 4-year-old female miniature pincher with a 40-day history of weight loss, lethargy and vomiting was referred to Small Animal Hospital, Faculty of Veterinary Medicine, University of Tehran. The case also had severe jaundice, chronic diarrhoea and steatorrhoea. The efforts for saving the life of the case were not successful and finally the animal died of hypovolaemic shock and electrolyte imbal...

Pancreatic adenocarcinoma in a patient with relapsed Hodgkin’s lymphoma

After curative treatment of Hodgkin’s lymphoma, increased risk of certain solid tumors has been reported. To best of our knowledge this is the first report of metachronous pancreatic adenocarcinoma which developed outside the previous radiation field in a patient with relapse Hodgkin’s lymphoma. Herein we present an 81-year-old female who developed pancreatic adenocarcinoma four yea...

Outstanding Problems concerning the Global Electric Circuit

We revisit the problems related to the discrepancy between the observed amplitudes, of responses of the global circuit to inputs related to solar activity, as compared to modeled amplitudes. The solar activity modulates the latitude distribution of the cosmic ray flux. It also modulates the X-ray flux at middle to high latitudes in the stratosphere, that is due to Bremsstrahlung from MeV electr...